Pizza Panini With Mozzarella Pepperoni

Category: Tasty and Easy Sandwich Recipes

This panini brings together the best of pizza flavors between two slices of golden, toasted bread. Hearty bread or ciabatta is loaded with fresh mozzarella and pepperoni, then slathered with savory pizza sauce for classic Italian inspiration. Grilled until the cheese melts and the exterior turns crisp and golden, each bite is stretchy, cheesy, and bursting with bold flavor. Olive oil spray ensures a crunchy crust, while letting the ingredients shine. Perfect for lunch or a simple dinner, slice and serve hot from the panini press or grill pan.

Chef with a smile, ready to cook and serve.
Updated on Tue, 17 Jun 2025 15:28:45 GMT
A sandwich with cheese and tomatoes. Pin
A sandwich with cheese and tomatoes. | yummygusto.com

Craving all the best parts of pizza but want a quick fix you can savor at lunchtime This pizza panini is my go to answer for busy nights when the family wants something cheesy toasty and totally crave worthy without fussing with dough or long bake times

This recipe became a weeknight lifesaver when my kids begged for pizza but I did not feel like rolling out dough That crunchy golden crust hooked us for good

Ingredients

  • Hearty bread slices like sourdough or ciabatta: Gives sturdy bite and stands up to melting cheese Look for loaves with a crisp crust
  • Pizza sauce or marinara: Delivers all the herby tomato flavors of pizza in a spread Check for sauces with simple ingredients and rich tomato aroma
  • Fresh mozzarella cheese: Offers melty stretch and a clean creamy flavor Find balls that feel moist and slice easily
  • Pepperoni slices: Classic for a peppery punch Opt for thin even rounds from the deli
  • Olive oil spray: Helps get a golden crisp exterior without extra greasiness Choose a high quality olive oil for best flavor

Step-by-Step Instructions

Prepare the Bread:
Slice your bread thick enough to support fillings about three quarters of an inch If using ciabatta pull out some of the inner bread by hand to make room for fillings without flattening the loaf
Sauce the Slices:
Spread a generous layer of pizza sauce over the inside of each bread slice Make sure to cover edge to edge so every bite is flavorful
Layer the Fillings:
Place sliced mozzarella evenly over one half of the bread then arrange pepperoni slices across the cheese Try not to crowd the edges so cheese will not ooze
Assemble and Spray:
Close up the sandwich with the other slice of bread Press gently then lightly coat both outer sides with olive oil spray for toasty crunch
Grill the Sandwich:
Place sandwich on your hot panini press or grill pan If you do not have a press use a heavy skillet to weigh it down Grill until the bread is deeply golden and the cheese inside is bubbling typically three to four minutes each side
Rest and Slice:
Let the panini rest for one to two minutes on a cutting board before slicing This helps the cheese settle so your sandwich holds together perfectly
A sandwich with cheese and tomato sauce.
A sandwich with cheese and tomato sauce. | yummygusto.com

Fresh mozzarella is the real game changer in this recipe Thanks to its stretchy melt my son declared it tasted just like pizza getting everyone to cheer at first bite

Storage Tips

Leftover pizza panini keeps best wrapped in foil and refrigerated for up to two days Reheat uncovered in a hot skillet or oven to revive that crispy texture Avoid microwaving which softens the crust

Ingredient Substitutions

You can swap provolone or part skim mozzarella for fresh mozzarella if needed Thick bakery white or focaccia bread makes a good stand in for ciabatta Try turkey pepperoni or roasted veggies for a lighter or vegetarian take

Serving Suggestions

Slice into strips and dunk in extra marinara for a hands on treat Serve with a crisp green salad or roasted veggies to balance the richness For a fun twist top with arugula or basil right before serving

Cultural Context

Paninis are rooted in Italian snack culture where pressed sandwiches are filled with regional specialties Bringing in classic pizza flavors is a nod to Italian American ingenuity turning favorite comfort food into a quick handheld meal

A stack of grilled cheese sandwiches.
A stack of grilled cheese sandwiches. | yummygusto.com

Pizza panini nights always feel a little special at my house and that first bite when the cheese stretches is pure magic

Recipe Q&A

→ Can I use different bread types?

Yes, ciabatta, sourdough, or rustic country bread all work well. Choose a sturdy loaf for best results.

→ Is it necessary to use a panini press?

No, a grill pan with a heavy skillet to press the sandwich works just as well for crisping the bread.

→ What cheese melts best for this panini?

Fresh mozzarella melts beautifully, but feel free to try provolone or a blend for extra flavor.

→ Can I substitute other meats for pepperoni?

Absolutely—salami, ham, or cooked sausage are delicious alternatives for a custom touch.

→ How can I make this vegetarian?

Simply omit the pepperoni or swap in grilled veggies like roasted peppers or mushrooms for a meat-free version.

Pizza Panini Mozzarella Pepperoni

Toasted sandwiches with mozzarella, pepperoni, and tangy sauce on hearty bread for a quick cheesy lunch.

Prep Time
10 min
Cook Time
8 min
Total Time
18 min
By: Sandra

Category: Sandwich Creations

Skill Level: Easy

Cuisine: Italian-American

Yield: 2 Serves (Makes 2 large panini sandwiches)

Dietary Info: ~

What You'll Need

→ Bread

01 4 thick slices hearty bread or 1 loaf ciabatta (340–400 g)

→ Sauce

02 120 ml pizza sauce or marinara sauce

→ Cheese

03 115 g fresh mozzarella cheese, thinly sliced

→ Meat

04 85–115 g pepperoni slices

→ Oil

05 Olive oil spray

Directions

Step 01

Preheat a panini press, electric grill, or grill pan over medium heat.

Step 02

Slice bread into thick pieces or halve a loaf of ciabatta. Optionally, remove some of the crumb from the ciabatta to create space for the filling.

Step 03

Spread pizza sauce evenly over the cut sides of each bread slice. Layer mozzarella and pepperoni on the bottom half, then place the top half of the bread.

Step 04

Lightly coat the exterior of the sandwich with olive oil spray.

Step 05

Place the assembled sandwich onto the preheated grill or press. If using a grill pan, press the sandwich with a heavy skillet. Grill for 3–4 minutes per side until bread is golden and cheese is melted.

Step 06

Remove the panini from heat and allow it to cool for 1–2 minutes. Slice and serve warm.

Notes

  1. Allowing the panini to rest briefly after grilling enhances slicing and improves texture.

Gear Required

  • Panini press or electric grill
  • Grill pan
  • Heavy skillet
  • Bread knife

Allergy Details

Double-check ingredients for allergens. If you’re unsure, talk to a health pro.
  • Contains gluten, dairy, and may contain nitrates from processed meats

Nutrition Info (per serving)

Just for reference. It’s not a substitute for a nutritionist’s advice.
  • Calories: 725
  • Fat: 35 g
  • Carbs: 66 g
  • Protein: 29 g